Cargo is a great venue if you happen to like jazz, soul, hip hop, electonica and such like.
They have live acts several times a week but be sure to check the listings as they have a wide range of promoters which means it has a very varied music policy.
The outdoor courtyard is great in the summer and they often have barbques. In the winter they have the restaurant which serves average food at reasonable prices.
The one bad thing about this place is the layout of the club - its sort of split into 2 which means that if its at capacity and the band comes on everyone rushes into one half of the venue which can make it really really packed - I saw The Roots here once and whilst it was a great show it was wayyy too packed.